Background & goals: Bioreactors are sensible instruments which are used for economical, time-conserving and large-scale manufacturing of biomass from cell cultivation. They supply optimum environmental situations similar to pH and temperature required for acquiring most quantities of biomass. Nonetheless, there is no such thing as a proof within the literature on the large-scale cultivation of Leishmania infantum parasites within the bioreactor. Due to this fact, the current research was undertaken to develop a brand new strategy for acquiring L. infantum biomass by utilizing pH and temperature controllable stirred bioreactor and to match parasitic development kinetics with classical technique inside erlenmeyers.
Strategies: With a purpose to receive parasite biomass, a newly developed pH and temperature managed stirred bioreactor was used and its efficacy was in contrast with a graduated classical scale-up technique. Progress kinetics of parasites inside erlenmeyers and bioreactors have been decided by evaluating promastigote numbers utilizing haemocytometer. The graduated scale enlargement of tradition was adopted by T25 flask, T75 flask, and 1 L erlenmeyer, respectively.
Outcomes: Obtained outcomes confirmed a 10-fold improve within the variety of promastigotes throughout the typical tradition carried out in 700 ml medium, whereas parasite numbers elevated roughly 15 occasions as a consequence of preliminary inoculation quantities within the bioreactor tradition carried out within the 3.5 l medium. Thus, there was 7.5 occasions extra biomass assortment in bioreactor in comparison with classical technique.
Interpretation & conclusion: It’s postulated that fixed tradition pH and temperature within the bioreactor extends cultivation time. This might result in important improve in parasite numbers. Therefore, pH and temperature controllable bioreactors supplied acquisition of enough quantities of biomass in distinction to classical strategies. Due to this fact, this kind of bioreactors could substitute classical tradition strategies within the manufacturing of antigenic molecules for vaccine improvement.
Investigating associations between intestinal alterations and parasite load in response to Bifidobacterium spp. and Lactobacillus spp. abundance within the intestine microbiota of hamsters contaminated by Leishmania infantum
Background: Visceral leishmaniasis (VL) is a tropical uncared for illness with excessive related charges of mortality. A number of research have highlighted the significance of the intestinal tract (IT) and intestine microbiota (GM) within the host immunological protection. Knowledge within the literature on parasite life cycle and host immune protection towards VL are scarce concerning the results of an infection on the IT and GM.
Aims: This research aimed to research modifications noticed within the colon of Leishmania infantum-infected hamsters, together with alterations within the enteric nervous system (ENS) and GM (particularly, ranges of bifidobacteria and lactobacilli).
Strategies: Male hamsters have been inoculated with L. infantum and euthanised at 4 or eight months post-infection. Intestines have been processed for histological evaluation and GM evaluation. Quantitative polymerase chain response (qPCR) was carried out to quantify every group of micro organism: Bifidobacterium spp. (Bf) and Lactobacillus spp (LacB).
Findings: Contaminated hamsters confirmed histoarchitectural loss within the colon wall, with elevated thickness within the submucosa and the mucosa layer, in addition to higher numbers of intraepithelial lymphocytes. Varieties suggestive of amastigotes have been seen inside mononuclear cells. L. infantum an infection induced modifications in ENS, as evidenced by will increase within the space of colonic enteric ganglia. Regardless of the absence of modifications within the ranges of Bf and LacB in the course of the course of an infection, the relative abundance of those micro organism was related to parasite load and histological alterations.
Quick-Course Remedy With Imipramine Entrapped in Squalene Liposomes Leads to Sterile Treatment of Experimental Visceral Leishmaniasis Induced by Antimony Resistant Leishmania donovani With Elevated Efficacy
Beforehand we now have proven that long run oral remedy of tricyclic-antidepressant-drug, imipramine, towards experimental visceral leishmaniasis, ends in clearance of organ parasites, no matter enter an infection, both with antimony-sensitive or antimony-resistant Leishmania donovani scientific isolates.
Though steady imipramine monotherapy for 28 days ends in important clearance of organ parasites in each SbR and SbSLD contaminated hamsters, the dose for the sterile parasite clearance from visceral organ is relatively increased (10 mg/kg) and reveals indicators of toxicity. Therefore, to scale back the toxicity, we encapsulated imipramine in squalene-phosphatidylcholine (SP) liposome (Lip-Imi) and examined its efficacy for a short-course remedy (10 days) within the animal mannequin of visceral leishmaniasis. We noticed a big discount of hepatic toxicity coupled with sterile parasite clearance in case of this short-course remedy of Lip-Imi, which is absent with free Imi remedy.
 LEISHMANIA CHAGASI, Protein |
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| abx061391-1mg | Abbexa | 1 mg | EUR 1762 |
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 Leishmania major PCR kit |
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| PCR-H687-48D | Bioingentech | 50T | EUR 425.8 |
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Description: An conventional PCR kit for detection of Leishmania major |
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Leishmania major PCR kit |
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| PCR-H687-96D | Bioingentech | 100T | EUR 521.5 |
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Description: An conventional PCR kit for detection of Leishmania major |
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 Leishmania tropica PCR kit |
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| PCR-H688-48D | Bioingentech | 50T | EUR 425.8 |
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Description: An conventional PCR kit for detection of Leishmania tropica |
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Leishmania tropica PCR kit |
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| PCR-H688-96D | Bioingentech | 100T | EUR 521.5 |
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Description: An conventional PCR kit for detection of Leishmania tropica |
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 Leishmania sp PCR kit |
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| PCR-VH087-48D | Bioingentech | 50T | EUR 425.8 |
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Description: An conventional PCR kit for detection of Leishmania sp |
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Leishmania sp PCR kit |
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| PCR-VH087-96D | Bioingentech | 100T | EUR 521.5 |
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Description: An conventional PCR kit for detection of Leishmania sp |
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 Leishmania infantum PCR kit |
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| PCR-VH100-48D | Bioingentech | 50T | EUR 425.8 |
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Description: An conventional PCR kit for detection of Leishmania infantum |
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Leishmania infantum PCR kit |
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| PCR-VH100-96D | Bioingentech | 100T | EUR 521.5 |
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Description: An conventional PCR kit for detection of Leishmania infantum |
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 Recombinant Leishmania Chagasi Protein |
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| VAng-Wyb7412-1mg | Creative Biolabs | 1 mg | EUR 3542 |
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Description: Leishmania Chagasi recombinant protein. |
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 Antibody) Leishmania Major Surface Protease gp63 (Leishmanolysin) Antibody |
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| abx415772-05ml | Abbexa | 0.5 ml | EUR 718 |
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 Recombinant Leishmania donovani KMP11 antigen |
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| DAG2700 | Creative Diagnostics | 1mg | EUR 1495 |
 Leishmania tropica RT PCR kit |
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| RTq-H680-150D | Bioingentech | 150T | EUR 701 |
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Description: A Real-Time PCR kit for detection of Leishmania tropica . |
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 Leishmania major RT PCR kit |
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| RTq-H687-100D | Bioingentech | 100T | EUR 628.5 |
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Description: A Real-Time PCR kit for detection of Leishmania major . |
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Leishmania major RT PCR kit |
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| RTq-H687-150D | Bioingentech | 150T | EUR 701 |
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Description: A Real-Time PCR kit for detection of Leishmania major . |
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Leishmania major RT PCR kit |
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| RTq-H687-50D | Bioingentech | 50T | EUR 532.8 |
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Description: A Real-Time PCR kit for detection of Leishmania major . |
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Leishmania tropica RT PCR kit |
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| RTq-H688-100D | Bioingentech | 100T | EUR 628.5 |
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Description: A Real-Time PCR kit for detection of Leishmania tropica . |
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Leishmania tropica RT PCR kit |
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| RTq-H688-50D | Bioingentech | 50T | EUR 532.8 |
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Description: A Real-Time PCR kit for detection of Leishmania tropica . |
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 Leishmania sp RT PCR kit |
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| RTq-VH087-100D | Bioingentech | 100T | EUR 628.5 |
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Description: A Real-Time PCR kit for detection of Leishmania sp . |
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Leishmania sp RT PCR kit |
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| RTq-VH087-150D | Bioingentech | 150T | EUR 701 |
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Description: A Real-Time PCR kit for detection of Leishmania sp . |
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Leishmania sp RT PCR kit |
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| RTq-VH087-50D | Bioingentech | 50T | EUR 532.8 |
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Description: A Real-Time PCR kit for detection of Leishmania sp . |
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 Leishmania infantum RT PCR kit |
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| RTq-VH100-100D | Bioingentech | 100T | EUR 628.5 |
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Description: A Real-Time PCR kit for detection of Leishmania infantum . |
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Leishmania infantum RT PCR kit |
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| RTq-VH100-150D | Bioingentech | 150T | EUR 701 |
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Description: A Real-Time PCR kit for detection of Leishmania infantum . |
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Leishmania infantum RT PCR kit |
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| RTq-VH100-50D | Bioingentech | 50T | EUR 532.8 |
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Description: A Real-Time PCR kit for detection of Leishmania infantum . |
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 Rapid Leishmania Ab Test Kit |
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| RB2104 | Bionote | 1 box | EUR 127 |
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Description: Please check the datasheet of Rapid Leishmania Ab Test Kit before using the test. |
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 Recombinant Leishmania Amazonensis HSP83 Protein |
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| VAng-Wyb7373-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Amazonensis Heat shock protein 83, partial, recombinant protein. |
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 Recombinant Leishmania Chagasi TOP2 Protein |
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| VAng-Wyb7414-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Chagasi DNA topoisomerase 2, partial, recombinant protein. |
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 Recombinant Leishmania Donovani HSP70 Protein |
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| VAng-Wyb7423-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Donovani Heat shock 70 kDa protein, partial, recombinant protein. |
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 Monoclonal Antibody) Mouse Anti Leishmania Lpg (Repeat Epitope) Monoclonal Antibody |
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| DMABT-51429ML | Creative Diagnostics | 0.5 ml | EUR 944 |
 Recombinant Leishmania chagasi K39 lipoprotein antigen |
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| DAG2704 | Creative Diagnostics | 1mg | EUR 1495 |
 Leishmania major One-Step PCR kit |
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| Oneq-H687-100D | Bioingentech | 100T | EUR 747.4 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania major. |
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Leishmania major One-Step PCR kit |
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| Oneq-H687-150D | Bioingentech | 150T | EUR 838.75 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania major. |
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Leishmania major One-Step PCR kit |
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| Oneq-H687-50D | Bioingentech | 50T | EUR 628.5 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania major. |
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 Leishmania tropica One-Step PCR kit |
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| Oneq-H688-100D | Bioingentech | 100T | EUR 747.4 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania tropica. |
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Leishmania tropica One-Step PCR kit |
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| Oneq-H688-150D | Bioingentech | 150T | EUR 838.75 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania tropica. |
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Leishmania tropica One-Step PCR kit |
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| Oneq-H688-50D | Bioingentech | 50T | EUR 628.5 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania tropica. |
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 Leishmania sp One-Step PCR kit |
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| Oneq-VH087-100D | Bioingentech | 100T | EUR 747.4 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania sp. |
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Leishmania sp One-Step PCR kit |
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| Oneq-VH087-150D | Bioingentech | 150T | EUR 838.75 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania sp. |
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Leishmania sp One-Step PCR kit |
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| Oneq-VH087-50D | Bioingentech | 50T | EUR 628.5 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania sp. |
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 Leishmania infantum One-Step PCR kit |
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| Oneq-VH100-100D | Bioingentech | 100T | EUR 747.4 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania infantum. |
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Leishmania infantum One-Step PCR kit |
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| Oneq-VH100-150D | Bioingentech | 150T | EUR 838.75 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania infantum. |
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Leishmania infantum One-Step PCR kit |
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| Oneq-VH100-50D | Bioingentech | 50T | EUR 628.5 |
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania infantum. |
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 Recombinant Leishmania chagasi K39 Protein [His] |
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| VAng-Wyb8612-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania chagasi K39 protein (aa 680-955), recombinant protein from E. coli, 1.41 mg/mL. |
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 Recombinant Leishmania donovani KMP11 antigen, Biotin-conjugated |
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| DAG2698 | Creative Diagnostics | 1mg | EUR 1495 |
 Recombinant Bovine p85a Protein, Untagged, Leishmania-10ug |
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| QP12950-10ug | EnQuireBio | 10ug | EUR 463 |
 Recombinant Bovine p85a Protein, Untagged, Leishmania-20ug |
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| QP12950-20ug | EnQuireBio | 20ug | EUR 762 |
 Recombinant Bovine p85a Protein, Untagged, Leishmania-2ug |
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| QP12950-2ug | EnQuireBio | 2ug | EUR 218 |
 Recombinant Leishmania donovani KMP-11 Protein [His] |
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| VAng-Wyb8611-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania donovani Kinetoplast Membrane Protein 11 (KMP-11), recombinant protein from E. coli, 1.59 mg/mL. |
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 Recombinant Leishmania chagasi K39 lipoprotein antigen, Biotin-conjugated |
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| DAG2701 | Creative Diagnostics | 1mg | EUR 1495 |
) Leishmania donovani Transitional endoplasmic reticulum ATPase, putative (LDBPK_361420) |
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| 1-CSB-EP2530LOE | Cusabio |
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Description: Recombinant Leishmania donovani Transitional endoplasmic reticulum ATPase,putative(LDBPK_361420),partial expressed in E.coli |
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) Recombinant Leishmania Amazonensis gp63 Protein (aa 100-574) |
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| VAng-Wyb7372-100gBaculovirus | Creative Biolabs | 100 µg (Baculovirus) | EUR 4793 |
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Description: Leishmania Amazonensis Leishmanolysin, recombinant protein. |
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Recombinant Leishmania Amazonensis gp63 Protein (aa 100-574) |
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| VAng-Wyb7372-500gBaculovirus | Creative Biolabs | 500 µg (Baculovirus) | EUR 6195 |
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Description: Leishmania Amazonensis Leishmanolysin, recombinant protein. |
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Recombinant Leishmania Amazonensis gp63 Protein (aa 100-574) |
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| VAng-Wyb7372-50gBaculovirus | Creative Biolabs | 50 µg (Baculovirus) | EUR 3335 |
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Description: Leishmania Amazonensis Leishmanolysin, recombinant protein. |
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) Recombinant Leishmania Amazonensis NAGT Protein (aa 1-466) |
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| VAng-Wyb7374-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 5508 |
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Description: Leishmania Amazonensis UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, recombinant protein. |
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) Recombinant Leishmania Braziliensis FEN1 Protein (aa 1-395) |
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| VAng-Wyb7377-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4710 |
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Description: Leishmania Braziliensis Flap endonuclease 1, recombinant protein. |
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Recombinant Leishmania Braziliensis FEN1 Protein (aa 1-395) |
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| VAng-Wyb7377-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3335 |
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Description: Leishmania Braziliensis Flap endonuclease 1, recombinant protein. |
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Recombinant Leishmania Braziliensis FEN1 Protein (aa 1-395) |
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| VAng-Wyb7377-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2278 |
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Description: Leishmania Braziliensis Flap endonuclease 1, recombinant protein. |
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) Recombinant Leishmania Braziliensis HSP70 Protein (aa 1-228) |
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| VAng-Wyb7378-100gBaculovirus | Creative Biolabs | 100 µg (Baculovirus) | EUR 3954 |
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Description: Leishmania Braziliensis Heat shock 70 kDa protein, recombinant protein. |
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Recombinant Leishmania Braziliensis HSP70 Protein (aa 1-228) |
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| VAng-Wyb7378-500gBaculovirus | Creative Biolabs | 500 µg (Baculovirus) | EUR 5164 |
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Description: Leishmania Braziliensis Heat shock 70 kDa protein, recombinant protein. |
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Recombinant Leishmania Braziliensis HSP70 Protein (aa 1-228) |
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| VAng-Wyb7378-50gBaculovirus | Creative Biolabs | 50 µg (Baculovirus) | EUR 2773 |
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Description: Leishmania Braziliensis Heat shock 70 kDa protein, recombinant protein. |
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) Recombinant Leishmania Braziliensis ISP1 Protein (aa 1-146) |
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| VAng-Wyb7379-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3129 |
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Description: Leishmania Braziliensis Ecotin-like protein 1, recombinant protein. |
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Recombinant Leishmania Braziliensis ISP1 Protein (aa 1-146) |
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| VAng-Wyb7379-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2236 |
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Description: Leishmania Braziliensis Ecotin-like protein 1, recombinant protein. |
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Recombinant Leishmania Braziliensis ISP1 Protein (aa 1-146) |
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| VAng-Wyb7379-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1549 |
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Description: Leishmania Braziliensis Ecotin-like protein 1, recombinant protein. |
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) Recombinant Leishmania Braziliensis JBP1 Protein (aa 1-813) |
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| VAng-Wyb7380-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Thymine dioxygenase JBP1, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LBRM_05_0060 Protein (aa 1-833) |
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| VAng-Wyb7382-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Major vault protein, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LBRM_14_1360 Protein (aa 1-561) |
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| VAng-Wyb7383-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Bifunctional NAD (P) H-hydrate repair enzyme, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LBRM_16_0320 Protein (aa 1-698) |
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| VAng-Wyb7384-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis tRNA (guanine (37)-N1)-methyltransferase, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LBRM_20_5150 Protein (aa 1-344) |
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| VAng-Wyb7385-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4380 |
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Description: Leishmania Braziliensis 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, recombinant protein. |
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Recombinant Leishmania Braziliensis LBRM_20_5150 Protein (aa 1-344) |
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| VAng-Wyb7385-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3103 |
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Description: Leishmania Braziliensis 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, recombinant protein. |
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Recombinant Leishmania Braziliensis LBRM_20_5150 Protein (aa 1-344) |
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| VAng-Wyb7385-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2126 |
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Description: Leishmania Braziliensis 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM01_V2.0740 Protein (aa 1-403) |
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| VAng-Wyb7386-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4765 |
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Description: Leishmania Braziliensis Probable eukaryotic initiation factor 4A, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM01_V2.0740 Protein (aa 1-403) |
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| VAng-Wyb7386-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3363 |
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Description: Leishmania Braziliensis Probable eukaryotic initiation factor 4A, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM01_V2.0740 Protein (aa 1-403) |
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| VAng-Wyb7386-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2291 |
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Description: Leishmania Braziliensis Probable eukaryotic initiation factor 4A, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM04_V2.0780 Protein (aa 1-670) |
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| VAng-Wyb7387-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Pescadillo homolog, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM09_V2.1490 Protein (aa 1-187) |
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| VAng-Wyb7388-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM11_V2.0090 Protein (aa 1-743) |
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| VAng-Wyb7389-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Ribosome biogenesis protein BOP1 homolog, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM11_V2.0490 Protein (aa 1-406) |
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| VAng-Wyb7390-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4779 |
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Description: Leishmania Braziliensis ATPase ASNA1 homolog, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM11_V2.0490 Protein (aa 1-406) |
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| VAng-Wyb7390-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3377 |
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Description: Leishmania Braziliensis ATPase ASNA1 homolog, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM11_V2.0490 Protein (aa 1-406) |
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| VAng-Wyb7390-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2305 |
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Description: Leishmania Braziliensis ATPase ASNA1 homolog, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM13_V2.0970 Protein (aa 1-710) |
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| VAng-Wyb7391-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Adenylosuccinate synthetase, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM15_V2.0540 Protein (aa 1-154) |
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| VAng-Wyb7392-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3184 |
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Description: Leishmania Braziliensis Ecotin-like protein 2, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM15_V2.0540 Protein (aa 1-154) |
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| VAng-Wyb7392-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2278 |
|
Description: Leishmania Braziliensis Ecotin-like protein 2, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM15_V2.0540 Protein (aa 1-154) |
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| VAng-Wyb7392-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1563 |
|
Description: Leishmania Braziliensis Ecotin-like protein 2, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM15_V2.0550 Protein (aa 1-309) |
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| VAng-Wyb7393-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4160 |
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Description: Leishmania Braziliensis Ecotin-like protein 3, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM15_V2.0550 Protein (aa 1-309) |
|||
| VAng-Wyb7393-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2950 |
|
Description: Leishmania Braziliensis Ecotin-like protein 3, recombinant protein. |
|||
Recombinant Leishmania Braziliensis LbrM15_V2.0550 Protein (aa 1-309) |
|||
| VAng-Wyb7393-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2016 |
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Description: Leishmania Braziliensis Ecotin-like protein 3, recombinant protein. |
|||
) Recombinant Leishmania Braziliensis LbrM18_V2.0760 Protein (aa 1-470) |
|||
| VAng-Wyb7394-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Probable citrate synthase, mitochondrial, partial, recombinant protein. |
|||
) Recombinant Leishmania Braziliensis LbrM19_V2.0670 Protein (aa 1-379) |
|||
| VAng-Wyb7395-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Lipoyl synthase, mitochondrial, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM20_V2.0500 Protein (aa 1-831) |
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| VAng-Wyb7396-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Translation factor GUF1 homolog, mitochondrial, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM25_V2.1130 Protein (aa 1-236) |
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| VAng-Wyb7397-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3707 |
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Description: Leishmania Braziliensis Alpha-tubulin N-acetyltransferase, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM25_V2.1130 Protein (aa 1-236) |
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| VAng-Wyb7397-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2649 |
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Description: Leishmania Braziliensis Alpha-tubulin N-acetyltransferase, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM25_V2.1130 Protein (aa 1-236) |
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| VAng-Wyb7397-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1796 |
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Description: Leishmania Braziliensis Alpha-tubulin N-acetyltransferase, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM28_V2.2010 Protein (aa 1-225) |
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| VAng-Wyb7398-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3638 |
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Description: Leishmania Braziliensis Probable methylthioribulose-1-phosphate dehydratase, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM28_V2.2010 Protein (aa 1-225) |
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| VAng-Wyb7398-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2594 |
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Description: Leishmania Braziliensis Probable methylthioribulose-1-phosphate dehydratase, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM28_V2.2010 Protein (aa 1-225) |
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| VAng-Wyb7398-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1769 |
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Description: Leishmania Braziliensis Probable methylthioribulose-1-phosphate dehydratase, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM29_V2.0730 Protein (aa 1-276) |
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| VAng-Wyb7399-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Braziliensis Elongation factor Ts, mitochondrial, partial, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM32_V2.0440 Protein (aa 1-891) |
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| VAng-Wyb7400-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 8189 |
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Description: Leishmania Braziliensis Protein SEY1 homolog, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM34_V2.0430 Protein (aa 2-264) |
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| VAng-Wyb7401-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3872 |
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Description: Leishmania Braziliensis 40S ribosomal protein S3a, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM34_V2.0430 Protein (aa 2-264) |
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| VAng-Wyb7401-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2759 |
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Description: Leishmania Braziliensis 40S ribosomal protein S3a, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM34_V2.0430 Protein (aa 2-264) |
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| VAng-Wyb7401-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1879 |
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Description: Leishmania Braziliensis 40S ribosomal protein S3a, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM35_V2.5180 Protein (aa 1-374) |
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| VAng-Wyb7402-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4573 |
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Description: Leishmania Braziliensis Methylthioribose-1-phosphate isomerase, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM35_V2.5180 Protein (aa 1-374) |
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| VAng-Wyb7402-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3239 |
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Description: Leishmania Braziliensis Methylthioribose-1-phosphate isomerase, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM35_V2.5180 Protein (aa 1-374) |
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| VAng-Wyb7402-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2209 |
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Description: Leishmania Braziliensis Methylthioribose-1-phosphate isomerase, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM35_V2.5370 Protein (aa 1-246) |
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| VAng-Wyb7403-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3762 |
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Description: Leishmania Braziliensis 40S ribosomal protein SA, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM35_V2.5370 Protein (aa 1-246) |
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| VAng-Wyb7403-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2690 |
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Description: Leishmania Braziliensis 40S ribosomal protein SA, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM35_V2.5370 Protein (aa 1-246) |
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| VAng-Wyb7403-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1824 |
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Description: Leishmania Braziliensis 40S ribosomal protein SA, recombinant protein. |
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) Recombinant Leishmania Braziliensis LbrM35_V2.7020 Protein (aa 1-398) |
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| VAng-Wyb7404-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4724 |
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Description: Leishmania Braziliensis Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM35_V2.7020 Protein (aa 1-398) |
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| VAng-Wyb7404-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3335 |
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Description: Leishmania Braziliensis Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, recombinant protein. |
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Recombinant Leishmania Braziliensis LbrM35_V2.7020 Protein (aa 1-398) |
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| VAng-Wyb7404-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 2278 |
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Description: Leishmania Braziliensis Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, recombinant protein. |
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) Recombinant Leishmania Braziliensis LIP2 Protein (aa 1-105) |
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| VAng-Wyb7405-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 2869 |
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Description: Leishmania Braziliensis 60S acidic ribosomal protein P2, recombinant protein. |
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Recombinant Leishmania Braziliensis LIP2 Protein (aa 1-105) |
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| VAng-Wyb7405-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2058 |
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Description: Leishmania Braziliensis 60S acidic ribosomal protein P2, recombinant protein. |
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Recombinant Leishmania Braziliensis LIP2 Protein (aa 1-105) |
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| VAng-Wyb7405-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1425 |
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Description: Leishmania Braziliensis 60S acidic ribosomal protein P2, recombinant protein. |
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) Recombinant Leishmania Chagasi gp63 Protein (aa 98-574) |
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| VAng-Wyb7406-100gBaculovirus | Creative Biolabs | 100 µg (Baculovirus) | EUR 4793 |
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Description: Leishmania Chagasi Leishmanolysin, recombinant protein. |
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Recombinant Leishmania Chagasi gp63 Protein (aa 98-574) |
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| VAng-Wyb7406-500gBaculovirus | Creative Biolabs | 500 µg (Baculovirus) | EUR 6209 |
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Description: Leishmania Chagasi Leishmanolysin, recombinant protein. |
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Recombinant Leishmania Chagasi gp63 Protein (aa 98-574) |
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| VAng-Wyb7406-50gBaculovirus | Creative Biolabs | 50 µg (Baculovirus) | EUR 3335 |
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Description: Leishmania Chagasi Leishmanolysin, recombinant protein. |
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) Recombinant Leishmania Chagasi KIN Protein (aa 1-955) |
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| VAng-Wyb7409-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Leishmania Chagasi Kinesin-like protein K39, partial, recombinant protein. |
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) Recombinant Leishmania Chagasi LCP0 Protein (aa 1-322) |
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| VAng-Wyb7410-100gBaculovirus | Creative Biolabs | 100 µg (Baculovirus) | EUR 4270 |
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Description: Leishmania Chagasi 60S acidic ribosomal protein P0, recombinant protein. |
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Recombinant Leishmania Chagasi LCP0 Protein (aa 1-322) |
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| VAng-Wyb7410-500gBaculovirus | Creative Biolabs | 500 µg (Baculovirus) | EUR 5563 |
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Description: Leishmania Chagasi 60S acidic ribosomal protein P0, recombinant protein. |
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Recombinant Leishmania Chagasi LCP0 Protein (aa 1-322) |
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| VAng-Wyb7410-50gBaculovirus | Creative Biolabs | 50 µg (Baculovirus) | EUR 2979 |
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Description: Leishmania Chagasi 60S acidic ribosomal protein P0, recombinant protein. |
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) Recombinant Leishmania Chagasi PP2C Protein (aa 1-406) |
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| VAng-Wyb7411-100gBaculovirus | Creative Biolabs | 100 µg (Baculovirus) | EUR 4559 |
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Description: Leishmania Chagasi Protein phosphatase 2C, recombinant protein. |
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Recombinant Leishmania Chagasi PP2C Protein (aa 1-406) |
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| VAng-Wyb7411-500gBaculovirus | Creative Biolabs | 500 µg (Baculovirus) | EUR 5907 |
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Description: Leishmania Chagasi Protein phosphatase 2C, recombinant protein. |
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Recombinant Leishmania Chagasi PP2C Protein (aa 1-406) |
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| VAng-Wyb7411-50gBaculovirus | Creative Biolabs | 50 µg (Baculovirus) | EUR 3170 |
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Description: Leishmania Chagasi Protein phosphatase 2C, recombinant protein. |
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) Recombinant Leishmania Chagasi RPL11 Protein (aa 1-188) |
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| VAng-Wyb7413-100gBaculovirus | Creative Biolabs | 100 µg (Baculovirus) | EUR 3817 |
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Description: Leishmania Chagasi 60S ribosomal protein L11, recombinant protein. |
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This additionally correlates with important improve in serum availability of imipramine in case of Lip-Imi remedy as a consequence of sustained launch. Clearance of parasite was coupled with the polarization of antileishmanial immune repertoire from Th2 to Th1 after remedy with Lip-Imi in each SbRLD and SbSLD contaminated mouse fashions of LD an infection. This research confirmed that imipramine is efficient towards each SbSLD and SbRLD at a considerably decrease dose with decreased time course of remedy with none poisonous negative effects, when encapsulated in SP-liposome. Thus, the drug has the potential to be repurposed for the remedy of Kala-azar.