Large-scale cultivation of Leishmania infantum promastigotes in stirred bioreactor

Background & goals: Bioreactors are sensible instruments which are used for economical, time-conserving and large-scale manufacturing of biomass from cell cultivation. They supply optimum environmental situations similar to pH and temperature required for acquiring most quantities of biomass. Nonetheless, there is no such thing as a proof within the literature on the large-scale cultivation of Leishmania infantum parasites within the bioreactor. Due to this fact, the current research was undertaken to develop a brand new strategy for acquiring L. infantum biomass by utilizing pH and temperature controllable stirred bioreactor and to match parasitic development kinetics with classical technique inside erlenmeyers.
Strategies: With a purpose to receive parasite biomass, a newly developed pH and temperature managed stirred bioreactor was used and its efficacy was in contrast with a graduated classical scale-up technique. Progress kinetics of parasites inside erlenmeyers and bioreactors have been decided by evaluating promastigote numbers utilizing haemocytometer. The graduated scale enlargement of tradition was adopted by T25 flask, T75 flask, and 1 L erlenmeyer, respectively.
Outcomes: Obtained outcomes confirmed a 10-fold improve within the variety of promastigotes throughout the typical tradition carried out in 700 ml medium, whereas parasite numbers elevated roughly 15 occasions as a consequence of preliminary inoculation quantities within the bioreactor tradition carried out within the 3.5 l medium. Thus, there was 7.5 occasions extra biomass assortment in bioreactor in comparison with classical technique.
Interpretation & conclusion: It’s postulated that fixed tradition pH and temperature within the bioreactor extends cultivation time. This might result in important improve in parasite numbers. Therefore, pH and temperature controllable bioreactors supplied acquisition of enough quantities of biomass in distinction to classical strategies. Due to this fact, this kind of bioreactors could substitute classical tradition strategies within the manufacturing of antigenic molecules for vaccine improvement.

Investigating associations between intestinal alterations and parasite load in response to Bifidobacterium spp. and Lactobacillus spp. abundance within the intestine microbiota of hamsters contaminated by Leishmania infantum

Background: Visceral leishmaniasis (VL) is a tropical uncared for illness with excessive related charges of mortality. A number of research have highlighted the significance of the intestinal tract (IT) and intestine microbiota (GM) within the host immunological protection. Knowledge within the literature on parasite life cycle and host immune protection towards VL are scarce concerning the results of an infection on the IT and GM.
Aims: This research aimed to research modifications noticed within the colon of Leishmania infantum-infected hamsters, together with alterations within the enteric nervous system (ENS) and GM (particularly, ranges of bifidobacteria and lactobacilli).
Strategies: Male hamsters have been inoculated with L. infantum and euthanised at 4 or eight months post-infection. Intestines have been processed for histological evaluation and GM evaluation. Quantitative polymerase chain response (qPCR) was carried out to quantify every group of micro organism: Bifidobacterium spp. (Bf) and Lactobacillus spp (LacB).
Findings: Contaminated hamsters confirmed histoarchitectural loss within the colon wall, with elevated thickness within the submucosa and the mucosa layer, in addition to higher numbers of intraepithelial lymphocytes. Varieties suggestive of amastigotes have been seen inside mononuclear cells. L. infantum an infection induced modifications in ENS, as evidenced by will increase within the space of colonic enteric ganglia. Regardless of the absence of modifications within the ranges of Bf and LacB in the course of the course of an infection, the relative abundance of those micro organism was related to parasite load and histological alterations.
 Large-scale cultivation of Leishmania infantum promastigotes in stirred bioreactor
Large-scale cultivation of Leishmania infantum promastigotes in stirred bioreactor

Quick-Course Remedy With Imipramine Entrapped in Squalene Liposomes Leads to Sterile Treatment of Experimental Visceral Leishmaniasis Induced by Antimony Resistant Leishmania donovani With Elevated Efficacy

Beforehand we now have proven that long run oral remedy of tricyclic-antidepressant-drug, imipramine, towards experimental visceral leishmaniasis, ends in clearance of organ parasites, no matter enter an infection, both with antimony-sensitive or antimony-resistant Leishmania donovani  scientific isolates.
Though steady imipramine monotherapy for 28 days  ends in important clearance of organ parasites in each SbR and SbSLD contaminated hamsters, the dose for the sterile parasite clearance from visceral organ is relatively increased (10 mg/kg) and reveals indicators of toxicity. Therefore, to scale back the toxicity, we encapsulated imipramine in squalene-phosphatidylcholine (SP) liposome (Lip-Imi) and examined its efficacy for a short-course remedy (10 days) within the animal mannequin of visceral leishmaniasis. We noticed a big discount of hepatic toxicity coupled with sterile parasite clearance in case of this short-course remedy of Lip-Imi, which is absent with free Imi remedy.

LEISHMANIA CHAGASI, Protein

abx061391-1mg 1 mg
EUR 1762
  • Shipped within 5-10 working days.

Leishmania major PCR kit

PCR-H687-48D 50T
EUR 425.8
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania major

Leishmania major PCR kit

PCR-H687-96D 100T
EUR 521.5
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania major

Leishmania tropica PCR kit

PCR-H688-48D 50T
EUR 425.8
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania tropica

Leishmania tropica PCR kit

PCR-H688-96D 100T
EUR 521.5
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania tropica

Leishmania sp PCR kit

PCR-VH087-48D 50T
EUR 425.8
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania sp

Leishmania sp PCR kit

PCR-VH087-96D 100T
EUR 521.5
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania sp

Leishmania infantum PCR kit

PCR-VH100-48D 50T
EUR 425.8
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania infantum

Leishmania infantum PCR kit

PCR-VH100-96D 100T
EUR 521.5
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Leishmania infantum

Recombinant Leishmania Chagasi Protein

VAng-Wyb7412-1mg 1 mg
EUR 3542
Description: Leishmania Chagasi recombinant protein.

Leishmania Major Surface Protease gp63 (Leishmanolysin) Antibody

abx415772-05ml 0.5 ml
EUR 718
  • Shipped within 1 week.

Recombinant Leishmania donovani KMP11 antigen

DAG2700 1mg
EUR 1495

Leishmania tropica RT PCR kit

RTq-H680-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania tropica .

Leishmania major RT PCR kit

RTq-H687-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania major .

Leishmania major RT PCR kit

RTq-H687-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania major .

Leishmania major RT PCR kit

RTq-H687-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania major .

Leishmania tropica RT PCR kit

RTq-H688-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania tropica .

Leishmania tropica RT PCR kit

RTq-H688-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania tropica .

Leishmania sp RT PCR kit

RTq-VH087-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania sp .

Leishmania sp RT PCR kit

RTq-VH087-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania sp .

Leishmania sp RT PCR kit

RTq-VH087-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania sp .

Leishmania infantum RT PCR kit

RTq-VH100-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania infantum .

Leishmania infantum RT PCR kit

RTq-VH100-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania infantum .

Leishmania infantum RT PCR kit

RTq-VH100-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Leishmania infantum .

Rapid Leishmania Ab Test Kit

RB2104 1 box
EUR 127
Description: Please check the datasheet of Rapid Leishmania Ab Test Kit before using the test.

Recombinant Leishmania Amazonensis HSP83 Protein

VAng-Wyb7373-inquire inquire Ask for price
Description: Leishmania Amazonensis Heat shock protein 83, partial, recombinant protein.

Recombinant Leishmania Chagasi TOP2 Protein

VAng-Wyb7414-inquire inquire Ask for price
Description: Leishmania Chagasi DNA topoisomerase 2, partial, recombinant protein.

Recombinant Leishmania Donovani HSP70 Protein

VAng-Wyb7423-inquire inquire Ask for price
Description: Leishmania Donovani Heat shock 70 kDa protein, partial, recombinant protein.

Mouse Anti Leishmania Lpg (Repeat Epitope) Monoclonal Antibody

DMABT-51429ML 0.5 ml
EUR 944

Recombinant Leishmania chagasi K39 lipoprotein antigen

DAG2704 1mg
EUR 1495

Leishmania major One-Step PCR kit

Oneq-H687-100D 100T
EUR 747.4
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania major.

Leishmania major One-Step PCR kit

Oneq-H687-150D 150T
EUR 838.75
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania major.

Leishmania major One-Step PCR kit

Oneq-H687-50D 50T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania major.

Leishmania tropica One-Step PCR kit

Oneq-H688-100D 100T
EUR 747.4
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania tropica.

Leishmania tropica One-Step PCR kit

Oneq-H688-150D 150T
EUR 838.75
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania tropica.

Leishmania tropica One-Step PCR kit

Oneq-H688-50D 50T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania tropica.

Leishmania sp One-Step PCR kit

Oneq-VH087-100D 100T
EUR 747.4
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania sp.

Leishmania sp One-Step PCR kit

Oneq-VH087-150D 150T
EUR 838.75
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania sp.

Leishmania sp One-Step PCR kit

Oneq-VH087-50D 50T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania sp.

Leishmania infantum One-Step PCR kit

Oneq-VH100-100D 100T
EUR 747.4
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania infantum.

Leishmania infantum One-Step PCR kit

Oneq-VH100-150D 150T
EUR 838.75
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania infantum.

Leishmania infantum One-Step PCR kit

Oneq-VH100-50D 50T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leishmania infantum.

Recombinant Leishmania chagasi K39 Protein [His]

VAng-Wyb8612-inquire inquire Ask for price
Description: Leishmania chagasi K39 protein (aa 680-955), recombinant protein from E. coli, 1.41 mg/mL.

Recombinant Leishmania donovani KMP11 antigen, Biotin-conjugated

DAG2698 1mg
EUR 1495

Recombinant Bovine p85a Protein, Untagged, Leishmania-10ug

QP12950-10ug 10ug
EUR 463

Recombinant Bovine p85a Protein, Untagged, Leishmania-20ug

QP12950-20ug 20ug
EUR 762

Recombinant Bovine p85a Protein, Untagged, Leishmania-2ug

QP12950-2ug 2ug
EUR 218

Recombinant Leishmania donovani KMP-11 Protein [His]

VAng-Wyb8611-inquire inquire Ask for price
Description: Leishmania donovani Kinetoplast Membrane Protein 11 (KMP-11), recombinant protein from E. coli, 1.59 mg/mL.

Recombinant Leishmania chagasi K39 lipoprotein antigen, Biotin-conjugated

DAG2701 1mg
EUR 1495

Leishmania donovani Transitional endoplasmic reticulum ATPase, putative (LDBPK_361420)

1-CSB-EP2530LOE
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 13.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Leishmania donovani Transitional endoplasmic reticulum ATPase,putative(LDBPK_361420),partial expressed in E.coli

Recombinant Leishmania Amazonensis gp63 Protein (aa 100-574)

VAng-Wyb7372-100gBaculovirus 100 µg (Baculovirus)
EUR 4793
Description: Leishmania Amazonensis Leishmanolysin, recombinant protein.

Recombinant Leishmania Amazonensis gp63 Protein (aa 100-574)

VAng-Wyb7372-500gBaculovirus 500 µg (Baculovirus)
EUR 6195
Description: Leishmania Amazonensis Leishmanolysin, recombinant protein.

Recombinant Leishmania Amazonensis gp63 Protein (aa 100-574)

VAng-Wyb7372-50gBaculovirus 50 µg (Baculovirus)
EUR 3335
Description: Leishmania Amazonensis Leishmanolysin, recombinant protein.

Recombinant Leishmania Amazonensis NAGT Protein (aa 1-466)

VAng-Wyb7374-1mgEcoli 1 mg (E. coli)
EUR 5508
Description: Leishmania Amazonensis UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, recombinant protein.

Recombinant Leishmania Braziliensis FEN1 Protein (aa 1-395)

VAng-Wyb7377-1mgEcoli 1 mg (E. coli)
EUR 4710
Description: Leishmania Braziliensis Flap endonuclease 1, recombinant protein.

Recombinant Leishmania Braziliensis FEN1 Protein (aa 1-395)

VAng-Wyb7377-500gEcoli 500 µg (E. coli)
EUR 3335
Description: Leishmania Braziliensis Flap endonuclease 1, recombinant protein.

Recombinant Leishmania Braziliensis FEN1 Protein (aa 1-395)

VAng-Wyb7377-50gEcoli 50 µg (E. coli)
EUR 2278
Description: Leishmania Braziliensis Flap endonuclease 1, recombinant protein.

Recombinant Leishmania Braziliensis HSP70 Protein (aa 1-228)

VAng-Wyb7378-100gBaculovirus 100 µg (Baculovirus)
EUR 3954
Description: Leishmania Braziliensis Heat shock 70 kDa protein, recombinant protein.

Recombinant Leishmania Braziliensis HSP70 Protein (aa 1-228)

VAng-Wyb7378-500gBaculovirus 500 µg (Baculovirus)
EUR 5164
Description: Leishmania Braziliensis Heat shock 70 kDa protein, recombinant protein.

Recombinant Leishmania Braziliensis HSP70 Protein (aa 1-228)

VAng-Wyb7378-50gBaculovirus 50 µg (Baculovirus)
EUR 2773
Description: Leishmania Braziliensis Heat shock 70 kDa protein, recombinant protein.

Recombinant Leishmania Braziliensis ISP1 Protein (aa 1-146)

VAng-Wyb7379-1mgEcoli 1 mg (E. coli)
EUR 3129
Description: Leishmania Braziliensis Ecotin-like protein 1, recombinant protein.

Recombinant Leishmania Braziliensis ISP1 Protein (aa 1-146)

VAng-Wyb7379-500gEcoli 500 µg (E. coli)
EUR 2236
Description: Leishmania Braziliensis Ecotin-like protein 1, recombinant protein.

Recombinant Leishmania Braziliensis ISP1 Protein (aa 1-146)

VAng-Wyb7379-50gEcoli 50 µg (E. coli)
EUR 1549
Description: Leishmania Braziliensis Ecotin-like protein 1, recombinant protein.

Recombinant Leishmania Braziliensis JBP1 Protein (aa 1-813)

VAng-Wyb7380-inquire inquire Ask for price
Description: Leishmania Braziliensis Thymine dioxygenase JBP1, partial, recombinant protein.

Recombinant Leishmania Braziliensis LBRM_05_0060 Protein (aa 1-833)

VAng-Wyb7382-inquire inquire Ask for price
Description: Leishmania Braziliensis Major vault protein, partial, recombinant protein.

Recombinant Leishmania Braziliensis LBRM_14_1360 Protein (aa 1-561)

VAng-Wyb7383-inquire inquire Ask for price
Description: Leishmania Braziliensis Bifunctional NAD (P) H-hydrate repair enzyme, partial, recombinant protein.

Recombinant Leishmania Braziliensis LBRM_16_0320 Protein (aa 1-698)

VAng-Wyb7384-inquire inquire Ask for price
Description: Leishmania Braziliensis tRNA (guanine (37)-N1)-methyltransferase, partial, recombinant protein.

Recombinant Leishmania Braziliensis LBRM_20_5150 Protein (aa 1-344)

VAng-Wyb7385-1mgEcoli 1 mg (E. coli)
EUR 4380
Description: Leishmania Braziliensis 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, recombinant protein.

Recombinant Leishmania Braziliensis LBRM_20_5150 Protein (aa 1-344)

VAng-Wyb7385-500gEcoli 500 µg (E. coli)
EUR 3103
Description: Leishmania Braziliensis 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, recombinant protein.

Recombinant Leishmania Braziliensis LBRM_20_5150 Protein (aa 1-344)

VAng-Wyb7385-50gEcoli 50 µg (E. coli)
EUR 2126
Description: Leishmania Braziliensis 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM01_V2.0740 Protein (aa 1-403)

VAng-Wyb7386-1mgEcoli 1 mg (E. coli)
EUR 4765
Description: Leishmania Braziliensis Probable eukaryotic initiation factor 4A, recombinant protein.

Recombinant Leishmania Braziliensis LbrM01_V2.0740 Protein (aa 1-403)

VAng-Wyb7386-500gEcoli 500 µg (E. coli)
EUR 3363
Description: Leishmania Braziliensis Probable eukaryotic initiation factor 4A, recombinant protein.

Recombinant Leishmania Braziliensis LbrM01_V2.0740 Protein (aa 1-403)

VAng-Wyb7386-50gEcoli 50 µg (E. coli)
EUR 2291
Description: Leishmania Braziliensis Probable eukaryotic initiation factor 4A, recombinant protein.

Recombinant Leishmania Braziliensis LbrM04_V2.0780 Protein (aa 1-670)

VAng-Wyb7387-inquire inquire Ask for price
Description: Leishmania Braziliensis Pescadillo homolog, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM09_V2.1490 Protein (aa 1-187)

VAng-Wyb7388-inquire inquire Ask for price
Description: Leishmania Braziliensis Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM11_V2.0090 Protein (aa 1-743)

VAng-Wyb7389-inquire inquire Ask for price
Description: Leishmania Braziliensis Ribosome biogenesis protein BOP1 homolog, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM11_V2.0490 Protein (aa 1-406)

VAng-Wyb7390-1mgEcoli 1 mg (E. coli)
EUR 4779
Description: Leishmania Braziliensis ATPase ASNA1 homolog, recombinant protein.

Recombinant Leishmania Braziliensis LbrM11_V2.0490 Protein (aa 1-406)

VAng-Wyb7390-500gEcoli 500 µg (E. coli)
EUR 3377
Description: Leishmania Braziliensis ATPase ASNA1 homolog, recombinant protein.

Recombinant Leishmania Braziliensis LbrM11_V2.0490 Protein (aa 1-406)

VAng-Wyb7390-50gEcoli 50 µg (E. coli)
EUR 2305
Description: Leishmania Braziliensis ATPase ASNA1 homolog, recombinant protein.

Recombinant Leishmania Braziliensis LbrM13_V2.0970 Protein (aa 1-710)

VAng-Wyb7391-inquire inquire Ask for price
Description: Leishmania Braziliensis Adenylosuccinate synthetase, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM15_V2.0540 Protein (aa 1-154)

VAng-Wyb7392-1mgEcoli 1 mg (E. coli)
EUR 3184
Description: Leishmania Braziliensis Ecotin-like protein 2, recombinant protein.

Recombinant Leishmania Braziliensis LbrM15_V2.0540 Protein (aa 1-154)

VAng-Wyb7392-500gEcoli 500 µg (E. coli)
EUR 2278
Description: Leishmania Braziliensis Ecotin-like protein 2, recombinant protein.

Recombinant Leishmania Braziliensis LbrM15_V2.0540 Protein (aa 1-154)

VAng-Wyb7392-50gEcoli 50 µg (E. coli)
EUR 1563
Description: Leishmania Braziliensis Ecotin-like protein 2, recombinant protein.

Recombinant Leishmania Braziliensis LbrM15_V2.0550 Protein (aa 1-309)

VAng-Wyb7393-1mgEcoli 1 mg (E. coli)
EUR 4160
Description: Leishmania Braziliensis Ecotin-like protein 3, recombinant protein.

Recombinant Leishmania Braziliensis LbrM15_V2.0550 Protein (aa 1-309)

VAng-Wyb7393-500gEcoli 500 µg (E. coli)
EUR 2950
Description: Leishmania Braziliensis Ecotin-like protein 3, recombinant protein.

Recombinant Leishmania Braziliensis LbrM15_V2.0550 Protein (aa 1-309)

VAng-Wyb7393-50gEcoli 50 µg (E. coli)
EUR 2016
Description: Leishmania Braziliensis Ecotin-like protein 3, recombinant protein.

Recombinant Leishmania Braziliensis LbrM18_V2.0760 Protein (aa 1-470)

VAng-Wyb7394-inquire inquire Ask for price
Description: Leishmania Braziliensis Probable citrate synthase, mitochondrial, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM19_V2.0670 Protein (aa 1-379)

VAng-Wyb7395-inquire inquire Ask for price
Description: Leishmania Braziliensis Lipoyl synthase, mitochondrial, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM20_V2.0500 Protein (aa 1-831)

VAng-Wyb7396-inquire inquire Ask for price
Description: Leishmania Braziliensis Translation factor GUF1 homolog, mitochondrial, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM25_V2.1130 Protein (aa 1-236)

VAng-Wyb7397-1mgEcoli 1 mg (E. coli)
EUR 3707
Description: Leishmania Braziliensis Alpha-tubulin N-acetyltransferase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM25_V2.1130 Protein (aa 1-236)

VAng-Wyb7397-500gEcoli 500 µg (E. coli)
EUR 2649
Description: Leishmania Braziliensis Alpha-tubulin N-acetyltransferase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM25_V2.1130 Protein (aa 1-236)

VAng-Wyb7397-50gEcoli 50 µg (E. coli)
EUR 1796
Description: Leishmania Braziliensis Alpha-tubulin N-acetyltransferase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM28_V2.2010 Protein (aa 1-225)

VAng-Wyb7398-1mgEcoli 1 mg (E. coli)
EUR 3638
Description: Leishmania Braziliensis Probable methylthioribulose-1-phosphate dehydratase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM28_V2.2010 Protein (aa 1-225)

VAng-Wyb7398-500gEcoli 500 µg (E. coli)
EUR 2594
Description: Leishmania Braziliensis Probable methylthioribulose-1-phosphate dehydratase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM28_V2.2010 Protein (aa 1-225)

VAng-Wyb7398-50gEcoli 50 µg (E. coli)
EUR 1769
Description: Leishmania Braziliensis Probable methylthioribulose-1-phosphate dehydratase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM29_V2.0730 Protein (aa 1-276)

VAng-Wyb7399-inquire inquire Ask for price
Description: Leishmania Braziliensis Elongation factor Ts, mitochondrial, partial, recombinant protein.

Recombinant Leishmania Braziliensis LbrM32_V2.0440 Protein (aa 1-891)

VAng-Wyb7400-1mgEcoli 1 mg (E. coli)
EUR 8189
Description: Leishmania Braziliensis Protein SEY1 homolog, recombinant protein.

Recombinant Leishmania Braziliensis LbrM34_V2.0430 Protein (aa 2-264)

VAng-Wyb7401-1mgEcoli 1 mg (E. coli)
EUR 3872
Description: Leishmania Braziliensis 40S ribosomal protein S3a, recombinant protein.

Recombinant Leishmania Braziliensis LbrM34_V2.0430 Protein (aa 2-264)

VAng-Wyb7401-500gEcoli 500 µg (E. coli)
EUR 2759
Description: Leishmania Braziliensis 40S ribosomal protein S3a, recombinant protein.

Recombinant Leishmania Braziliensis LbrM34_V2.0430 Protein (aa 2-264)

VAng-Wyb7401-50gEcoli 50 µg (E. coli)
EUR 1879
Description: Leishmania Braziliensis 40S ribosomal protein S3a, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.5180 Protein (aa 1-374)

VAng-Wyb7402-1mgEcoli 1 mg (E. coli)
EUR 4573
Description: Leishmania Braziliensis Methylthioribose-1-phosphate isomerase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.5180 Protein (aa 1-374)

VAng-Wyb7402-500gEcoli 500 µg (E. coli)
EUR 3239
Description: Leishmania Braziliensis Methylthioribose-1-phosphate isomerase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.5180 Protein (aa 1-374)

VAng-Wyb7402-50gEcoli 50 µg (E. coli)
EUR 2209
Description: Leishmania Braziliensis Methylthioribose-1-phosphate isomerase, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.5370 Protein (aa 1-246)

VAng-Wyb7403-1mgEcoli 1 mg (E. coli)
EUR 3762
Description: Leishmania Braziliensis 40S ribosomal protein SA, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.5370 Protein (aa 1-246)

VAng-Wyb7403-500gEcoli 500 µg (E. coli)
EUR 2690
Description: Leishmania Braziliensis 40S ribosomal protein SA, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.5370 Protein (aa 1-246)

VAng-Wyb7403-50gEcoli 50 µg (E. coli)
EUR 1824
Description: Leishmania Braziliensis 40S ribosomal protein SA, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.7020 Protein (aa 1-398)

VAng-Wyb7404-1mgEcoli 1 mg (E. coli)
EUR 4724
Description: Leishmania Braziliensis Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.7020 Protein (aa 1-398)

VAng-Wyb7404-500gEcoli 500 µg (E. coli)
EUR 3335
Description: Leishmania Braziliensis Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, recombinant protein.

Recombinant Leishmania Braziliensis LbrM35_V2.7020 Protein (aa 1-398)

VAng-Wyb7404-50gEcoli 50 µg (E. coli)
EUR 2278
Description: Leishmania Braziliensis Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, recombinant protein.

Recombinant Leishmania Braziliensis LIP2 Protein (aa 1-105)

VAng-Wyb7405-1mgEcoli 1 mg (E. coli)
EUR 2869
Description: Leishmania Braziliensis 60S acidic ribosomal protein P2, recombinant protein.

Recombinant Leishmania Braziliensis LIP2 Protein (aa 1-105)

VAng-Wyb7405-500gEcoli 500 µg (E. coli)
EUR 2058
Description: Leishmania Braziliensis 60S acidic ribosomal protein P2, recombinant protein.

Recombinant Leishmania Braziliensis LIP2 Protein (aa 1-105)

VAng-Wyb7405-50gEcoli 50 µg (E. coli)
EUR 1425
Description: Leishmania Braziliensis 60S acidic ribosomal protein P2, recombinant protein.

Recombinant Leishmania Chagasi gp63 Protein (aa 98-574)

VAng-Wyb7406-100gBaculovirus 100 µg (Baculovirus)
EUR 4793
Description: Leishmania Chagasi Leishmanolysin, recombinant protein.

Recombinant Leishmania Chagasi gp63 Protein (aa 98-574)

VAng-Wyb7406-500gBaculovirus 500 µg (Baculovirus)
EUR 6209
Description: Leishmania Chagasi Leishmanolysin, recombinant protein.

Recombinant Leishmania Chagasi gp63 Protein (aa 98-574)

VAng-Wyb7406-50gBaculovirus 50 µg (Baculovirus)
EUR 3335
Description: Leishmania Chagasi Leishmanolysin, recombinant protein.

Recombinant Leishmania Chagasi KIN Protein (aa 1-955)

VAng-Wyb7409-inquire inquire Ask for price
Description: Leishmania Chagasi Kinesin-like protein K39, partial, recombinant protein.

Recombinant Leishmania Chagasi LCP0 Protein (aa 1-322)

VAng-Wyb7410-100gBaculovirus 100 µg (Baculovirus)
EUR 4270
Description: Leishmania Chagasi 60S acidic ribosomal protein P0, recombinant protein.

Recombinant Leishmania Chagasi LCP0 Protein (aa 1-322)

VAng-Wyb7410-500gBaculovirus 500 µg (Baculovirus)
EUR 5563
Description: Leishmania Chagasi 60S acidic ribosomal protein P0, recombinant protein.

Recombinant Leishmania Chagasi LCP0 Protein (aa 1-322)

VAng-Wyb7410-50gBaculovirus 50 µg (Baculovirus)
EUR 2979
Description: Leishmania Chagasi 60S acidic ribosomal protein P0, recombinant protein.

Recombinant Leishmania Chagasi PP2C Protein (aa 1-406)

VAng-Wyb7411-100gBaculovirus 100 µg (Baculovirus)
EUR 4559
Description: Leishmania Chagasi Protein phosphatase 2C, recombinant protein.

Recombinant Leishmania Chagasi PP2C Protein (aa 1-406)

VAng-Wyb7411-500gBaculovirus 500 µg (Baculovirus)
EUR 5907
Description: Leishmania Chagasi Protein phosphatase 2C, recombinant protein.

Recombinant Leishmania Chagasi PP2C Protein (aa 1-406)

VAng-Wyb7411-50gBaculovirus 50 µg (Baculovirus)
EUR 3170
Description: Leishmania Chagasi Protein phosphatase 2C, recombinant protein.

Recombinant Leishmania Chagasi RPL11 Protein (aa 1-188)

VAng-Wyb7413-100gBaculovirus 100 µg (Baculovirus)
EUR 3817
Description: Leishmania Chagasi 60S ribosomal protein L11, recombinant protein.
This additionally correlates with important improve in serum availability of imipramine in case of Lip-Imi remedy as a consequence of sustained launch. Clearance of parasite was coupled with the polarization of antileishmanial immune repertoire from Th2 to Th1 after remedy with Lip-Imi in each SbRLD and SbSLD contaminated mouse fashions of LD an infection. This research confirmed that imipramine is efficient towards each SbSLD and SbRLD at a considerably decrease dose with decreased time course of remedy with none poisonous negative effects, when encapsulated in SP-liposome. Thus, the drug has the potential to be repurposed for the remedy of Kala-azar.

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