Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major.

The Leishmania donovani complicated is taken into account to be composed of three species; L. donovani, L. infantum and L. chagasi, though this classification has been challenged. Genotypic relationships inside the complicated had been evaluated at totally different ranges by: binding of the probe Lmet9, particular for L.

 

chagasi and Outdated World Leishmania spp.; partial sequencing of a constitutive main floor protease single gene (mspC) and random amplification of polymorphic DNA (RAPD). The Outdated World Leishmania spp. and the L.

donovani complicated have a monophyletic origin. Leishmania chagasi clearly belongs to the L. donovani complicated however it’s indistinguishable from L. infantum, which suggests introduction of L. chagasi into the New World in current historical past.

Leishmania infantum/L. chagasi was recognized as a monophyletic group inside the L. donovani complicated however L. donovani could also be paraphyletic. Variety inside L. donovani is substantial and phylogeographical patterns of affiliation had been discovered.

 

Genomic affirmation of hybridisation and up to date inbreeding in a vector-isolated Leishmania inhabitants.

  • Though asexual replica through clonal propagation has been proposed because the principal reproductive mechanism throughout parasitic protozoa of the Leishmania genus, sexual recombination has lengthy been suspected, primarily based on hybrid marker profiles detected in area isolates from totally different geographical areas.
anti-Galectin 3
YF-PA12946 50 ug
EUR 363
Description: Mouse polyclonal to Galectin 3
anti-Galectin 3
YF-PA12947 100 ul
EUR 403
Description: Rabbit polyclonal to Galectin 3
anti-Galectin 3
YF-PA12948 100 ug
EUR 403
Description: Rabbit polyclonal to Galectin 3
anti-Galectin 8
YF-PA12951 50 ul
EUR 363
Description: Mouse polyclonal to Galectin 8
anti-Galectin 13
YF-PA18585 50 ug
EUR 363
Description: Mouse polyclonal to Galectin 13
anti-Galectin 3
YF-PA24079 50 ul
EUR 334
Description: Mouse polyclonal to Galectin 3
anti-galectin 9
YF-PA24081 50 ul
EUR 334
Description: Mouse polyclonal to galectin 9
Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280
Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280
Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280
Anti-human Galectin-3 antibody
STJ15100163 250 µg
EUR 336
Description: This monoclonal antibody is for studies of antigen expression in cells and tissue sections using immunocytochemistry and immunoprecipitation
Anti-Galectin-9 Antibody
A03415 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Galectin-9 Antibody (LGALS9) detection.tested for WB in Human, Mouse, Rat.
Anti-Galectin 1 Antibody
A00470-2 100ug/vial
EUR 294
anti- Galectin 2 antibody
FNab03310 100µg
EUR 585
Description: Antibody raised against Galectin 2
anti- Galectin 4 antibody
FNab03311 100µg
EUR 505.25
Description: Antibody raised against Galectin 4
anti- Galectin 8 antibody
FNab03312 100µg
EUR 505.25
Description: Antibody raised against Galectin 8
anti- Galectin 9 antibody
FNab03313 100µg
EUR 505.25
Description: Antibody raised against Galectin 9
anti- Galectin-1 antibody
FNab03314 100µg
EUR 505.25
Description: Antibody raised against Galectin-1
anti- Galectin-1 antibody
FNab03315 100µg
EUR 548.75
Description: Antibody raised against Galectin-1
anti- Galectin-3 antibody
FNab03316 100µg
EUR 505.25
Description: Antibody raised against Galectin-3
anti- Galectin-3 antibody
FNab03317 100µg
EUR 548.75
Description: Antibody raised against Galectin-3
anti- Galectin-7 antibody
FNab03318 100µg
EUR 505.25
Description: Antibody raised against Galectin-7
anti-Galectin-3 (6G2)
LF-MA20336 100 ug
EUR 354
Description: Mouse monoclonal to Galectin-3
Anti-Galectin 2 antibody
PAab03310 100 ug
EUR 412
Anti-Galectin 4 antibody
PAab03311 100 ug
EUR 355
Anti-Galectin 8 antibody
PAab03312 100 ug
EUR 355
Anti-Galectin 9 antibody
PAab03313 100 ug
EUR 355
Anti-Galectin-1 antibody
PAab03314 100 ug
EUR 355
Anti-Galectin-3 antibody
PAab03316 100 ug
EUR 355
Anti-Galectin-7 antibody
PAab03318 100 ug
EUR 355
Anti-Galectin-3 antibody
STJ16100369 1 mL
EUR 1047
Anti-Galectin-3 antibody
STJ16100782 100 µg
EUR 720
Anti-Galectin-1 antibody
STJ93201 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-1.
Anti-Galectin-2 antibody
STJ93202 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-2.
Anti-Galectin-4 antibody
STJ93203 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-4.
Anti-Galectin-7 antibody
STJ93204 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-7.
Anti-Galectin-8 antibody
STJ93205 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-8.
Anti-Galectin-9 antibody
STJ93206 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-9.
Anti-Galectin 3 antibody
STJ73098 100 µg
EUR 359
Anti-Galectin-3 antibody
STJ180106 0.1 ml
EUR 212
Anti-Galectin 3 antibody
STJ190057 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to Galectin 3 (AS1A24)
Anti-Galectin-3 antibody
STJ96945 200 µl
EUR 197
Description: Galectin-3 is a protein encoded by the LGALS3 gene which is approximately 26,1 kDa. Galectin-3 is localised to the cytoplasm and nucleus. It is involved in NF-kappaB signalling, advanced glycosylation end product receptor signalling and cell adhesion. It is a galactose-specific lectin which binds IgE and may mediate the stimulation by CSPG4 of endothelial cells migration along with the alpha-3, beta-1 integrin. It is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. Galectin-3 is expressed mainly in the colonic epithelium and is also abundantly expressed in activated macrophages. Mutations in the LGALS3 gene may result in follicular adenoma and thyroid cancer. STJ96945 was developed from clone 6G2 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous galectin-3 proteins.
Anti-Galectin-3 antibody
STJ97549 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3 (6B8).
Anti-Galectin-3 antibody
STJ97550 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3 (8D7).
Anti-Galectin-3 antibody
STJ97551 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3 (5D9).
Anti-Galectin-3 antibody
STJ97601 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3 (2F9).
Anti-Galectin-3 antibody
STJ97604 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3 (16E6).
Anti-Galectin-3 antibody
STJ97605 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3 (1H4).
Anti-Galectin-3 antibody
STJ97715 200 µl
EUR 197
Description: Mouse monoclonal to Galectin-3.
Anti-Galectin-1 antibody
STJ98716 200 µl
EUR 197
Description: Rabbit polyclonal to Galectin-1.
Anti-Galectin 1 (1A8)
YF-MA13984 100 ug
EUR 363
Description: Mouse monoclonal to Galectin 1
Anti-Galectin 8 (3E5)
YF-MA13986 100 ug
EUR 363
Description: Mouse monoclonal to Galectin 8
Anti Human Galectin-3 Polyclonal Antibody
KH040
EUR 649
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur.
Anti-Galectin 10/CLC Antibody
A01350 100ug/vial
EUR 294
Anti-Galectin 1/Lgals1 Antibody
A00470 100ug/vial
EUR 334
Anti-Galectin 1/Lgals1 Antibody
A00470-1 100ug/vial
EUR 334
Anti-Galectin 1 Biotinylated Antibody
A00470-Biotin 50ug/vial
EUR 294
Anti-Galectin 1/LGALS1 Antibody
PA1422 100ug/vial
EUR 334
anti-Galectin 1 (1E8-1B2)
LF-MA10174 100 ug
EUR 363
Description: Mouse monoclonal to Galectin 1
Anti-Galectin 1 Monoclonal Antibody
M00470-1 100ug
EUR 397
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.
Anti-Galectin-3 Monoclonal Antibody
M00621-1 100ul
EUR 397
Description: Mouse Monoclonal Galectin-3 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.
Anti-Galectin 3/LGALS3 Antibody
PB9081 100ug/vial
EUR 334
Anti-Galectin 1/LGALS1 Antibody
PB9240 100ug/vial
EUR 334
Anti-Galectin 1/LGALS1 Antibody
PB9240-1 100ug/vial
EUR 334
Anti-Galectin 3/LGALS3 Antibody
PB9279 100ug/vial
EUR 334
Anti-Galectin 8/LGALS8 Antibody
PB9659 100ug/vial
EUR 294
Anti-galectin 9/LGALS9 Antibody
PB9660 100ug/vial
EUR 294
Anti-Galectin-3 10301 antibody
STJ400238 1 mg
EUR 446
Anti-Galectin-3 10302 antibody
STJ400239 1 mg
EUR 446
Anti-Galectin-3 10303 antibody
STJ400240 1 mg
EUR 446
  • The current experimental demonstration of a sexual cycle in Leishmania inside sand flies has confirmed the prevalence of hybridisation, however information of the parasite life cycle within the wild nonetheless stays restricted.

 

  • Right here, we use complete genome sequencing to analyze the frequency of sexual replica in Leishmania, by sequencing the genomes of 11 Leishmania infantum isolates from sand flies and 1 affected person isolate in a spotlight of cutaneous leishmaniasis within the Çukurova province of southeast Turkey. That is the primary genome-wide examination of a vector-isolated inhabitants of Leishmania parasites. A genome-wide sample of patchy heterozygosity and SNP density was noticed each inside particular person strains and throughout the entire group.

 

  • Comparisons with different Leishmania donovani complicated genome sequences counsel that these isolates are derived from a single cross of two numerous strains with subsequent recombination inside the inhabitants.

 

  • This interpretation is supported by a statistical mannequin of the genomic variability for every pressure in comparison with the L. infantum reference genome pressure in addition to genome-wide scans for recombination inside the inhabitants. Additional evaluation of those heterozygous blocks signifies that the 2 mother and father had been phylogenetically distinct. Patterns of linkage disequilibrium point out that this inhabitants reproduced primarily clonally following the unique hybridisation occasion, however that some recombination additionally occurred.

 

  • This statement allowed us to estimate the relative charges of sexual and asexual replica inside this inhabitants, to our information the primary quantitative estimate of those occasions through the Leishmania life cycle.

CD 437

B6785-25 25 mg
EUR 347
Description: CD 437 is a selective agonist of RAR? [1]. Retinoic acid receptor gamma (RAR-?) is a nuclear receptor that is activated by 9-cis retinoic acid and all-trans retinoic acid. RAR-? also functions as a transcription factor.

CD 437

B6785-5 5 mg
EUR 145
Description: CD 437 is a selective agonist of RAR? [1]. Retinoic acid receptor gamma (RAR-?) is a nuclear receptor that is activated by 9-cis retinoic acid and all-trans retinoic acid. RAR-? also functions as a transcription factor.

CD 437

B6785-50 50 mg
EUR 596
Description: CD 437 is a selective agonist of RAR? [1]. Retinoic acid receptor gamma (RAR-?) is a nuclear receptor that is activated by 9-cis retinoic acid and all-trans retinoic acid. RAR-? also functions as a transcription factor.

CD 2314

B5483-10 10 mg
EUR 405
Description: CD 2314 is a potent and selective agonist of RAR? with Kd value of 145 and >3760 nM for RAR? and RAR? receptors, respectively [1]. Retinoic acid receptor ? (RAR?) is a nuclear receptor for retinoic acid and localizes to the cytoplasm and subnuclear compartments.

CD 2314

B5483-50 50 mg
EUR 1502
Description: CD 2314 is a potent and selective agonist of RAR? with Kd value of 145 and >3760 nM for RAR? and RAR? receptors, respectively [1]. Retinoic acid receptor ? (RAR?) is a nuclear receptor for retinoic acid and localizes to the cytoplasm and subnuclear compartments.

CD 1530

B7102-10 10 mg
EUR 251
Description: Target: RAR?, RAR? and RAR?Ki: 150, 1500, and 2750 nMCD1530 is a potent and selective RAR receptor agonist with Ki values of 150, 1500 and 2750 nM for RAR?, RAR? and RAR? receptors, respectively [1].

CD 1530

B7102-5 5 mg
EUR 166
Description: Target: RAR?, RAR? and RAR?Ki: 150, 1500, and 2750 nMCD1530 is a potent and selective RAR receptor agonist with Ki values of 150, 1500 and 2750 nM for RAR?, RAR? and RAR? receptors, respectively [1].

CD 3254

B7352-10 10 mg
EUR 293
Description: CD3254 is a potent and selective agonist of Retinoid X receptors (RXR?).

CD 3254

B7352-5 5 mg
EUR 180
Description: CD3254 is a potent and selective agonist of Retinoid X receptors (RXR?).

CD 2665

B7501-10 10 mg
EUR 293
Description: CD 2665 is a retinoic acid receptor ? (RAR?) / RAR? antagonist [1] [2] [3] with binding Kd values of 306 nM and 110 nM to RAR? and RAR?, respectively [3].Retinoic acid receptors include RAR?, RAR? and RAR?.

CD 2665

B7501-5 5 mg
EUR 196
Description: CD 2665 is a retinoic acid receptor ? (RAR?) / RAR? antagonist [1] [2] [3] with binding Kd values of 306 nM and 110 nM to RAR? and RAR?, respectively [3].Retinoic acid receptors include RAR?, RAR? and RAR?.

CD 2665

B7501-50 50 mg
EUR 1001
Description: CD 2665 is a retinoic acid receptor ? (RAR?) / RAR? antagonist [1] [2] [3] with binding Kd values of 306 nM and 110 nM to RAR? and RAR?, respectively [3].Retinoic acid receptors include RAR?, RAR? and RAR?.

CD-3

GK8139-25G 25 g
EUR 69

Rabbit CD-44(CD-44) ELISA Kit

QY-E30297 96T
EUR 374

Human CD ELISA Kit

EHC0084 96Tests
EUR 521

CD-14, human recombinant

4937-10
EUR 370

SBE-β-CD

HY-17031 500mg
EUR 108

gp130/CD 130

GT15072 100 ug
EUR 526

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Human CD 99 ELISA kit

E01C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD 99 ELISA kit

E01C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD 99 ELISA kit

E01C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

anti-5Methylcytosine antibody mouse IgM (clone 5MC-CD)

51-003 100ug
EUR 414
Description: The anti-5Methylcytosine antibody mouse IgM (clone 5MC-CD) is available in Europe and for worldwide shipping via Gentaur.

Mouse Monoclonal Anti-Human CD3 FITC/CD(16+56) PE

CD03-D1-50 50 tests
EUR 651

Goat CD ELISA Kit

EGTC0084 96Tests
EUR 521

Canine CD ELISA Kit

ECC0084 96Tests
EUR 521

Bovine CD ELISA Kit

EBC0084 96Tests
EUR 521

Anserini CD ELISA Kit

EAC0084 96Tests
EUR 521

Porcine CD ELISA Kit

EPC0084 96Tests
EUR 521

Rat CD ELISA Kit

ERC0084 96Tests
EUR 521

Rabbit CD ELISA Kit

ERTC0084 96Tests
EUR 521

Mouse CD ELISA Kit

EMC0084 96Tests
EUR 521

CD-14, mouse recombinant

4938-10
EUR 479

CD-14 Antibody (CT)

6732-100
EUR 316

CD-14 Antibody (NT)

6733-100
EUR 316

CD-45 Antibody (CT)

6734-100
EUR 316

AXYGEN® CASTING DAMS FOR USE WITH 10 CM GEL BOX, SET OF 2

HGB10-CD 1/pk
EUR 73
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® CASTING DAMS FOR USE WITH 15 CM GEL BOX, SET OF 2

HGB15-CD 1/pk
EUR 73
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® CASTING DAMS FOR USE WITH 20 CM GEL BOX, SET OF 2

HGB20-CD 1/pk
EUR 82
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® CASTING DAMS FOR USE WITH 7 CM GEL BOX, SET OF 2

HGB7-CD 1/pk
EUR 63
Description: Lab Equipment; Axygen Branded EQ

Human CD 40 Ligand ELISA kit

E01C0018-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human CD 40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD 40 Ligand ELISA kit

E01C0018-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human CD 40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD 40 Ligand ELISA kit

E01C0018-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human CD 40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Soluble CD 44v9 ELISA kit

E01C0053-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human Soluble CD 44v9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Soluble CD 44v9 ELISA kit

E01C0053-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human Soluble CD 44v9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Soluble CD 44v9 ELISA kit

E01C0053-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human Soluble CD 44v9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD 36 (Soluble) ELISA Kit

DEIA6943 96T
EUR 1022
Description: FOR THE QUANTITATIVE DETERMINATION OF HUMAN SOLUBLE CD36 CONCENTRATIONS IN PLASMA AND CELL CULTURE SUPERNATES. ;Human soluble CD36 (sCD36) immunoassay is a 3.5 - 4.5 hour solid phase ELISA designed to measure human sCD36 in cell culture supernates and

Polyclonal CD-14 Antibody (CT)

APR00356G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CD-14 (CT). This antibody is tested and proven to work in the following applications:

Polyclonal CD-14 Antibody (NT)

APR00357G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CD-14 (NT). This antibody is tested and proven to work in the following applications:

Polyclonal CD-45 Antibody (CT)

APR00358G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CD-45 (CT). This antibody is tested and proven to work in the following applications:

Goat CD 99 ELISA kit

E06C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Goat CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD 99 ELISA kit

E06C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Goat CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD 99 ELISA kit

E06C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Goat CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat CD 99 ELISA kit

E02C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat CD 99 ELISA kit

E02C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat CD 99 ELISA kit

E02C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse CD 99 ELISA kit

E03C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse CD 99 ELISA kit

E03C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse CD 99 ELISA kit

E03C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit CD 99 ELISA kit

E04C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit CD 99 ELISA kit

E04C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit CD 99 ELISA kit

E04C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rabbit CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig CD 99 ELISA kit

E07C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Porcine CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig CD 99 ELISA kit

E07C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Porcine CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig CD 99 ELISA kit

E07C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Porcine CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey CD 99 ELISA kit

E09C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey CD 99 ELISA kit

E09C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey CD 99 ELISA kit

E09C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig CD ELISA Kit

EGC0084 96Tests
EUR 521

Dog CD 99 ELISA kit

E08C0337-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Canine CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog CD 99 ELISA kit

E08C0337-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Canine CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog CD 99 ELISA kit

E08C0337-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Canine CD 99 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse control serum, CD-1

NMOS-CD1-1 1 ml
EUR 103

Mouse control serum, CD-1

NMOS-CD1-5 5 ml
EUR 164
  • The host immune response has a important function not solely in safety from human leishmaniasis but additionally in selling illness severity. Though candidate gene approaches in mouse fashions of leishmaniasis have been extraordinarily informative, a worldwide understanding of the immune pathways lively in lesions from human sufferers is missing.

 

  • To deal with this situation, genome-wide transcriptional profiling of Leishmania braziliensis-infected cutaneous lesions and regular pores and skin controls was carried out. A signature of the L. braziliensis pores and skin lesion was outlined, which incorporates over 2,000 differentially regulated genes.

 

  • Pathway-level evaluation of this transcriptional response revealed key organic pathways current in cutaneous lesions, producing a testable ‘metapathway‘ mannequin of immunopathology and offering new insights for therapy of human leishmaniasis.

 

  • We now have remoted and characterised a differentially-regulated gene household within the protozoan parasite Leishmania main. The household comprises 5 genes linked inside a 10Kb area of the genome: three of the genes are carefully associated in DNA sequence, the opposite two have solely restricted homology.

 

  • Publish-transcriptional management of the differential expression sample is usually recommended by detection of precursor RNA molecules containing intergenic sequences and proof that mature mRNA molecules comprise a 35nt spliced chief sequence at their 5′ ends. These options assist a mannequin of polycistronic transcription through which the steadiness and differential processing of precursor RNA molecules decide the regular state ranges of mature mRNA.

 

  • We now have recognized a number of DNA sequence motifs inside the gene household which have potential roles in differential processing and/or RNA stability: an alternate 5′ splice acceptor web site for trans-splicing; a putative polyadenylation web site; and a area of potential secondary construction inside 3′ flanking sequences. The three’ sequence parts are conserved in these genes that share the identical sample of differential regulation. To our information, that is the primary instance of coordinated differential-regulation of a non-identical gene cluster in Leishmania.

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